Matthew Watson

Matthew Watson

Company: Merck & Co

Job title: Principal Scientist

Seminars:

Chair’s Closing Remarks 3:40 pm

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day: Conference Day Two

Roundtable Discussion: Optimizing Analytical Development to Create a Toolkit for De-Risking Critical Stages in Plasmid DNA Production 1:40 pm

How to develop fit-for-use analytics to enable comprehensive plasmid characterization and assessing suitability for downstream therapeutic applications How to implement a targeted testing approach to minimize redundancy and streamline the plasmid development process by focusing on critical checkpoints How can we tailor analytical testing to enable consistent quality for both off-the-shelf and personalized plasmids?Read more

day: Conference Day Two

Chair’s Opening Remarks 8:50 am

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day: Conference Day Two

Maximizing the Recovery of Plasmid DNA: Accelerating Workflow to Increase the Efficiency of Lysis & DNA Extraction 3:45 pm

Developing efficient lysis procedures tailored to plasmid DNA extraction to reduce genomic DNA contamination Controlling important parameters to reduce shearing stress on plasmid DNA and promote a high yield of unbroken plasmids Closely monitoring parameters such as pH, buffer choice, and salt concentrations to prepare the extract for purificationRead more

day: Conference Day One

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