Column-Free DNA Production: Tackling Scalability Challenges

  • Exploring poultry H5N1 vaccine breakthroughs using column-free processes with >95% supercoiled DNA and proven long-term stability
  • Learning GMP scale-up lessons from 50L to 1000L fermentation batches while navigating regulatory requirements for novel platforms
  • Analyzing process economics and applying real-world facility implementation strategies for resin versus resin-free production