Debottlenecking Vaccine Manufacturing; Simplifying DSP Process
Time: 12:15 pm
day: Day One
Details:
- Optimizing host strain, plasmid design, media composition and fermentation conditions for high biomass, plasmid yield and quality, facilitating downstream purification of ScpDNA
- pDNA recovery is a critical step in the downstream process, removing most contaminants while concentrating pDNA
- Pharmaceutical pDNA has stringent requirements of purity, homogeneity, and efficacy, and SC pDNA is the most stable, efficient, and biologically active